What is the classification of pharmaceutical raw materials?

Pharmaceutical raw materials are various substances prepared by chemical synthesis, plant extraction or biotechnology for use as medicinal powders, crystals, extracts, etc., but which patients cannot directly take. The main characteristic of pharmaceutical raw materials is that they cannot be directly used for clinical use. It is a raw material, and only after processing can it become a pharmaceutical preparation, and then according to experiments, it can become a medicine for clinical application.

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Pharmaceutical raw material classification

Pharmaceutical raw materials are divided into chemical synthetic drugs and natural chemical drugs according to their sources. Chemical synthetic drugs can be further divided into inorganic synthetic drugs and organic synthetic drugs. Inorganic synthetic drugs are inorganic compounds (very few elements), such as aluminum hydroxide and magnesium trisilicate for the treatment of gastric and duodenal ulcers; organic synthetic drugs are mainly composed of basic organic chemical materials, through a series of organic Drugs produced by chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.).

(1) Natural chemicals

Natural chemical drugs are mainly from nature, which can be divided into biochemical drugs and phytochemicals. Biochemical drugs mainly refer to those obtained through biological processing. For example, antibiotics are generally produced by microbial fermentation and belong to the category of biochemistry. A variety of semi-synthetic antibiotics that have emerged in recent years are products that combine biosynthesis and chemical synthesis. Among the raw materials, the proportion of organic synthetic drugs, the output and the output value account for the largest proportion, which is the main pillar of the chemical pharmaceutical industry. The quality of raw materials determines the quality of the preparations. Therefore, the quality standards are very strict. Countries around the world have established strict national pharmacopoeia standards and quality control methods for their widely used APIs.

(2) Chemical synthetic drugs

With the rapid development of the chemical raw material medicine industry, chemical raw materials have also become a major source, and of course, competition among different enterprises has also increased. Nowadays, M&A integration and capital operation among large-scale chemical raw materials companies are becoming more and more frequent. Domestic excellent chemical raw material drug manufacturers are paying more and more attention to the research of the industry market, especially the in-depth study on the development environment of enterprises and the changes in customer demand trends. Because of this, a large number of domestic excellent chemical raw material medicine brands have risen rapidly and gradually become the leader in the chemical raw material medicine industry. China is a major producer of APIs. In 2012, the output of APIs was 1.36 million tons, an increase of 9.05% year-on-year, and production ranked first in the world. The economies of scale benefited from the low cost and environmental pollution produced in China. In the current situation that China’s prices generally rise and environmental management continues to strengthen, the cost advantage of industry development becomes less obvious.

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