L-Epinephrine hydrochloride (CAS 55-31-2)

Wuhan mengqi Biotechnology Co. Ltd is a Pharmaceutical raw materials suppliers.We can provide bulk CAS 55-31-2CAS 55-31-2 in stock.
L-Epinephrine hydrochloride Chemical PropertiesIUPAC Name: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol hydrochloride
Synonyms of L-Epinephrine hydrochloride (CAS NO.55-31-2): (-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride ; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride ; Adrenalin chloride ; Epinephrine chloride ; l-Methylaminoethanolcathechol hydrochloride
CAS NO: 55-31-2
Molecular Formula: C9H14ClNO3
Molecular Weight: 219.67
Molecular Structure:
EINECS: 200-230-3
H bond acceptors: 4
H bond donors: 4
Freely Rotating Bonds: 6
Polar Surface Area: 30.93 Å2
Flash Point: 207.9 °C
Melting Poin: 157°C
Boiling Point: 413.1 °C at 760 mmHg
Enthalpy of Vaporization: 70.21 kJ/mol
Vapour Pressure: 1.45E-07 mmHg at 25°C
Appearance: crystals
SMILES: Cl.Oc1ccc(cc1O)[C@@H](O)CNC
InChI: InChI=1/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H/t9-;/m0./s1
InChIKey: ATADHKWKHYVBTJ-FVGYRXGTBN
Std. InChI: InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H/t9-;/m0./s1
Std. InChIKey: ATADHKWKHYVBTJ-FVGYRXGTSA-N
L-Epinephrine hydrochloride Toxicity Data With Reference

OrganismTest TypeRouteReported Dose (Normalized Dose)EffectSourceguinea pigLDLointravenous200ug/kg (0.2mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963.
guinea pigLDLosubcutaneous2mg/kg (2mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963.
mouseLD50intraperitoneal4664ug/kg (4.664mg/kg)VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTIONJournal of Pharmacology and Experimental Therapeutics. Vol. 90, Pg. 110, 1947.
mouseLD50intravenous140ug/kg (0.14mg/kg)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: DYSPNEAEuropean Journal of Pharmacology. Vol. 9, Pg. 289, 1970.
mouseLD50subcutaneous1980ug/kg (1.98mg/kg)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENTJournal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 214, 1946.
mouseLDLooral50mg/kg (50mg/kg) Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963.
ratLD50intraduodenal35mg/kg (35mg/kg) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
ratLD50oral24mg/kg (24mg/kg) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
ratLD50subcutaneous5mg/kg (5mg/kg) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
ratLDLointravenous50ug/kg (0.05mg/kg)BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSJournal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925.

L-Epinephrine hydrochloride Consensus ReportsReported in NTP Carcinogenesis Studies (Inhalation); Inadequate Study: rat, mouse NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-380 ,1990. .
L-Epinephrine hydrochloride Safety ProfilePoison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also VASOTONIN and other adrenalin compounds.
Safety Information aboout L-Epinephrine hydrochloride (CAS NO.55-31-2):
RIDADR: 3249
HazardClass: 6.1(a)
PackingGroup: II
L-Epinephrine hydrochloride SpecificationHealth Hazard of L-Epinephrine hydrochloride (CAS 55-31-2): Adverse reactions include restlessness; anxiety; headache; tremor; weakness; dizziness; pallor; respiratory difficulties; palpitation; nausea and vomiting.

发表评论

Fill in your details below or click an icon to log in:

WordPress.com 徽标

You are commenting using your WordPress.com account. Log Out /  更改 )

Google+ photo

You are commenting using your Google+ account. Log Out /  更改 )

Twitter picture

You are commenting using your Twitter account. Log Out /  更改 )

Facebook photo

You are commenting using your Facebook account. Log Out /  更改 )

Connecting to %s

%d 博主赞过:
search previous next tag category expand menu location phone mail time cart zoom edit close